Close the shut-off valve on the propane gas tank.
Using an adjustable wrench, remove the gas supply hose from the manifold.
Disconnect the gas supply hose from the propane tank.
Remove the cotter pin that secures the gas supply hose to the frame of the grill. Pull the hose and regulator off of the grill and set them aside for disposal.
Connect the new hose to the manifold on the grill. Hook up the other end of the hose to the propane tank.
Open the valve on the propane tank to restore the gas supply. To check for leaks, use a clean paint brush to apply soapy water (50/50 mild detergent such as dish soap and water) to the manifold fitting and the gas tank fitting. Bubbles on the soapy solution indicate a gas leak. Tighten the fittings if necessary to close the leaks.